At age eight, David watched as his father was killed by an Epic, a human with superhuman powers, and now, ten years later, he joins the Reckoners–the only people who are trying to kill the Epics and end their tyranny.
While preparing for the most dreaded assignment at the prestigious Irving School, the Tragedy Paper, Duncan gets wrapped up in the tragic tale of Tim Macbeth, a former student who had a clandestine relationship with the wrong girl, and his own ill-fated romance with Daisy.
Seventeen-year-old Greg has managed to become part of every social group at his Pittsburgh high school without having any friends, but his life changes when his mother forces him to befriend Rachel, a girl he once knew in Hebrew school who has leukemia.
Feeling cast off when her best friend outgrows their shared love for a favorite celebrity, Cath, a dedicated fan-fiction writer, struggles to survive on her own in her first year of college while avoiding a surly roommate, bonding with a handsome classmate who only wants to talk about words, and worrying about her fragile father.
After a series of suicide-killings and a deadly storm, the residents of the town of Oleander, Kansas, start acting even more strangely than would be expected. Only the 5 witnesses of the murders retain their sound minds, and must band together to save the town from whatever has come over it.